Poliovirus Receptor (CD155) Expression in Pediatric Brain Tumors Mediates Oncolysis of Medulloblastoma and Pleomorphic Xanthoastrocytoma

Poliovirus oncolytic immunotherapy is a putatively novel approach to treat pediatric brain tumors. This work sought to determine expression of the poliovirus receptor (PVR), CD155, in low-grade and malignant pediatric brain tumors and its ability to infect, propagate, and inhibit cell proliferation. CD155 expression in pleomorphic xanthoastrocytoma (PXA), medulloblastoma, atypical teratoid rhabdoid tumor, primitive neuroectodermal […]

Venezuela: PAHO on the suspected polio cases

From <http://crofsblogs.typepad.com/h5n1/2018/06/venezuela-paho-on-the-suspected-polio-cases.html#> PAHO has published Epidemiological Update: Detection of Sabin type 3 vaccine poliovirus in a case of Acute Flaccid Paralysis. The situation summary: On 7 June 2018, the World Health Organization (WHO) International Health Regulations (IHR) Regional Contact Point received an unofficial report on the detection of Sabin type 3 vaccine poliovirus in a sample […]

Memorial Dedicated to FDR’s Disability Will Feature Personal Tributes to People with Disabilities – Disabled World

Sculpture of President Franklin D. Roosevelt greeting a young girl who is also disabled, will be the first memorial dedicated to FDR disability Source: Memorial Dedicated to FDR’s Disability Will Feature Personal Tributes to People with Disabilities – Disabled World Published 2016-07-05 Author: Marc Diamond, Chair, FDR Hope Memorial Committee – Contact: fdrhopememorial.org Quote: “How […]

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Polio Pioneer Helps Survivors Hold On To Strength : NPR

People come from around the world to see Dr. Lauro Halstead. He’s one of only a handful of doctors in the U.S. who specializes in polio, and he was one of the first to spread the word about post-polio syndrome, a condition that affects polio survivors. Halstead has special insight into the challenges of the […]

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Perlman: Trump gesture about disabled reporter ‘terrible’ | U.S. News | US News

JERUSALEM (AP) — Violinist Itzhak Perlman, a longtime advocate for the disabled, is still upset over Donald Trump’s derisive behavior toward a disabled reporter last fall and says he’ll support Hillary Clinton in November’s election. Source: Perlman: Trump gesture about disabled reporter ‘terrible’ | U.S. News | US News By JOSEF FEDERMAN, Associated Press JERUSALEM […]

European Polio Union and PSA RAG join forces [Press Release]

Press Release by EPU/RAG on co-operation to assist Polio Survivors Poliomyelitis is a disease that is on the edge of eradication in the world thanks to the combined efforts of Rotary International, the World Health Organization, UNICEF, Centers for Disease Control (CDC) and the Bill & Melinda Gates Foundation (& other generous funders), together with […]